Special Issue on Chronic Kidney Disease in Children

Submission Deadline: Feb. 20, 2020

Please click the link to know more about Manuscript Preparation: http://www.ajpediatrics.org/submission

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Special Issue Flyer (PDF)
  • Lead Guest Editor
    • Ilkhamdzhan Karimdzhanov
      Tashkent Medical Academy, Tashkent, Uzbekistan
  • Guest Editor
    Guest Editors play a significant role in a special issue. They maintain the quality of published research and enhance the special issue’s impact. If you would like to be a Guest Editor or recommend a colleague as a Guest Editor of this special issue, please Click here to complete the Guest Editor application.
    • Lola Rachmanova
      Tashkent Medical Academy, Tashkent, Uzbekistan
    • Turdicul Bobomuratov
      Tashkent Medical Academy, Tashkent, Uzbekistan
    • Gulshan Iskanova
      Tashkent Medical Academy, Tashkent, Uzbekistan
    • Anvar Tursunbaev
      Tashkent Medical Academy, Tashkent, Uzbekistan
    • Umida Zokirova
      Tashkent Medical Academy, Tashkent, Uzbekistan
    • Gulnoza Yusupova
      Tashkent Medical Academy, Tashkent, Uzbekistan
  • Introduction

    Chronic kidney disease (CKD) has been suggested to affect 15–74.7 children per mil-lion globally. Although CKD is relatively rare in children as compared with adults, hypertension (HTN), obesity and metabolic syndrome, uric acid disturbances is highly prevalent. The prevalence of HTN, obesity and metabolic syndrome is tenfold higher than in the general pediatric population and known to increase as children progress through the stages of CKD, so that by the time they are on dialysis. CKD HTN, obesity, metabolic syndrome and uric acid metabolism are intrinsically linked. Thus, decreased kidney function may be directly related to increased BP, overweight and metabolic syndrome. There are now many studies demonstrating an interaction between CKD and HTN, overweight and metabolic syndrome likely hastening the progression of CKD toward end-stage renal disease. Addressing HTN, overweight and obesity may well prevent or abrogate this decline in renal function and have, therefore, become imperative in the management of CKD. As well as being an associated feature and complication of CKD, and independent risk factors for CKD progression, HTN, obesity, metabolic syndrome and disturbances of uric acid metabolism also contributes to cardiovascular mortality in these children.
    Adopting best practices for monitoring and controlling body weight, BP are crucial to improve the management of obesity, HTN, and prevent future end-organ damage. However, diagnosing and managing HTN and obesity in pediatric CKD patients remains a challenge. When obesity and HTN are diagnosed, antihypertensive drugs, including angiotensin converting enzyme (ACE) inhibitors, antiobesity medications such as orlistat might offer renoprotection and delay the progression of CKD, especially in proteinuric states. Dietary restriction and monitoring is also a factor in managing obesity and HTN, but has proved difficult to control in the pediatric population.
    To study the role of hypertension, obesity, metabolic syndrome and uric acid disturbances in progression of chronic kidney disease in children.
    Aims and Scope:
    1. Chronic kidney diseases
    2. Hypertension
    3. Overweight
    4. Obesity
    5. Metabolic syndrome
    6. Uric acid

  • Guidelines for Submission

    Manuscripts can be submitted until the expiry of the deadline. Submissions must be previously unpublished and may not be under consideration elsewhere.

    Papers should be formatted according to the guidelines for authors (see: http://www.ajpediatrics.org/submission). By submitting your manuscripts to the special issue, you are acknowledging that you accept the rules established for publication of manuscripts, including agreement to pay the Article Processing Charges for the manuscripts. Manuscripts should be submitted electronically through the online manuscript submission system at http://www.sciencepublishinggroup.com/login. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal and will be listed together on the special issue website.

  • Published Papers

    The special issue currently is open for paper submission. Potential authors are humbly requested to submit an electronic copy of their complete manuscript by clicking here.